Carriage of extended-spectrum beta-lactamase–producing Enterobacteriaceae and the risk of surgical site infection after colorectal surgery: a prospective cohort study

B Dubinsky-Pertzov, E Temkin… - Clinical Infectious …, 2019 - academic.oup.com
Background Antibiotic prophylaxis that covers enteric pathogens is essential in preventing
surgical site infections (SSIs) after colorectal surgery. Current prophylaxis regimens do not
cover extended-spectrum beta-lactamase–producing Enterobacteriaceae (ESBL-PE). We
aimed to determine whether the risk of SSI following colorectal surgery is higher in ESBL-PE
carriers than in noncarriers. Methods We conducted a prospective cohort study of patients
who underwent elective colorectal surgery in 3 hospitals in Israel, Switzerland, and Serbia …
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